HIV/AIDS is an Immune System Disorder in which the body’s ability to defend itself against infections, is greatly diminished. HIV is spread primarily through sexual or blood-to-blood contact. To put this simply, in layman’s terms, the HIV virus enters the bloodstream and attaches itself to the service of a white blood cell (the CD4 cell’s receptors). The virus then changes its genetic information into that of the white blood cell. The virus cannot be recognized by other white blood cells and is, over time, able to replicate itself into hundreds of HIV viruses. When the HIV virus has used the cellular material of the white blood cell, this breaks open and the new virus can, and does, spread through the bloodstream.
A person infected with HIV can go through four stages of the disease:
1. Primary HIV infection stage
2. A symptomatic latent phase
3. Minor symptomatic phase
4. Major symptomatic phase
5. AIDS defining conditions; the severe symptomatic stage.
Symptoms of Stage 1 are:
• Sore throat, headache, mild fever, fatigue, muscle and joint pains, swelling of the lymph nodes, rash, and mouth ulcerations.
The CD4 cell count is approx. 800-1200 cells/mm3.
Symptoms of Stage 2 are:
• No symptoms occur as this is the latent stage.
The CD4 cell count is between 500 and 800 cells
Symptoms of Stage 3 are:
• Swelling of the lymph nodes/glands in the neck, armpits and groin.
• Occasional fevers, recurrent chest infections.
• Shingles, skin infections and rashes.
• Recurrent mouth ulcers
• Weight loss up to 10% of the person’s usual body weight.
• Prolonged, unexplained fatigue.
The CD4 count is between 350 and 500 cells
Symptoms of Stage 4 are:
• Persistent and recurrent oral and vaginal Candida infections (thrush)
• Recurrent herpes infections eg cold sores
• Recurrent shingles infections (herpes zoster)
• Recurrent bacterial skin infections and skin rashes
• Fever that lasts for more than a month, night sweats » Read more: Living With HIV-AIDS – Important General Information For a Better Quality of Life
