Archive for the ‘Diseases’ category

New Evidence Shows That HIV Rarely Spreads Heterosexually

August 15th, 2011

In the developing world, the virus has existed for at least 65 years because HIV is rarely spread heterosexually. Research that studied the wives of infected hemophiliacs showed that an HIV-positive person requires over 1,000 unprotected sexual contacts with an HIV-negative person from the opposite sex to pass along the virus just once.In another surprise study, published in the Lancet, 1997, 349:851-2, French doctors at the Cochin-Port Royal hospital in Paris looked at the risk of married couples wanting to conceive a baby where the man was HIV-positive. Their findings are in line with infection rates of 1 per 1000 acts of unprotected sex among stable heterosexual couples.

According to this published research, it would take an HIV-infected heterosexual who has sexual intercourse 2-3 times a week about seven years to infect another person with HIV! This practically means that it would take the HIV-infected males of one million couples 2,739 years of daily unprotected sex to infect all female partners.In the developing world, unprotected sex among heterosexuals cannot, therefore, be held responsible for the high number of people who test HIV positive (even if HIV tests were 100% reliable, which they are not).

How is AIDS contracted?

However, the situation is different with regard to infected pregnant women. A baby is directly and constantly exposed to the mother’s blood for a period of 9 months. During this period the virus has a 50% chance of being passed on to the baby. Retroviruses survive when they reach a new host prenatally (passed from mother to child). This way of passing on a virus is at least 500 times more efficient than through sexual transmission. (Blood transfusion is another obvious way of contracting the virus)

In contrast to the situation in wealthy nations, HIV in Third World countries is equally distributed between both sexes, which means, it must have been passed on from mother to child for many centuries. Had HIV been a deadly killer virus, the babies of infected mothers would have obviously been born deformed, miscarried, or dead, because newly born babies have not yet developed adequate immunity to defend themselves against a killer virus. Even if they somehow managed to survive, they could only last for a maximum of two years – the latency period given to infected babies before developing AIDS. The spreading of the virus would have stopped automatically through the destruction of all new babies that were infected by their mothers.

Due to the low rates of homosexuality in developing countries, the prenatal route of transmission has been their only efficient way (50 percent chance) to pass on HIV to the new generations. Grown female children who become mothers would again have a 50 percent chance of passing the virus to their children. Therefore, in Africa alone, HIV must have been around for many generations before it was able to infect as many as 6-8 million people. The latest argument that the increased condom use in some African nations helped to slow the rate of infection is hardly convincing since the main route of HIV infection in Africa is from mother to child.

Who Gets AIDS?

The situation is much different in the industrialized world where HIV is mostly transmitted through different routes. The most susceptible groups are very active homosexuals, needle-sharing heroin addicts, and hemophiliacs who receive transfusions. They represent the main and easiest routes through which disease-causing microbes can be passed on to others who share one common risk factor: immune deficiency. In other words, the groups in society where HIV is commonly present amongst their members are also the groups with the biggest health risks and, therefore, more likely to produce AIDS symptoms. Still, HIV’s most concentrated occurrence among health risk groups cannot be blamed for causing AIDS diseases, just as elevated cholesterol levels cannot be held responsible for causing heart disease. These are mere correlations. Another problem is that gay men, drug users, and hemophiliacs who are exposed to semen, drugs, blood transfusions, hepatitis, the Epstein Barr virus, and many other diseases or factors known to cause biological false positives in HIV tests, represent the most unreliable groups in society to demonstrate real presence of HIV.

As prophesied 13 years ago, AIDS has invaded the heterosexual community, or so it appears. Since cervical cancer and other female diseases have more recently been renamed AIDS diseases, AIDS seems to have affected the female population. However, most AIDS patients are still male.

Anything and everything that strongly abuses the body and depletes the immune system must be held responsible for causing illness, regardless of whether it is a stroke, cancer, or an AIDS disease. Emotional stress, insufficient nutrition, dehydration, sleep deprivation, alcohol, cigarettes, antibiotics, hard drugs, excessive sexual activity, etc., can all damage the immune system. A dormant piece of viral material such as HIV, on the other hand, can do no harm in a healthy body.

Whoever continuously exposes himself to immune risk factors is also more susceptible to developing the Acquired Human Immune Deficiency Syndrome. Someone may argue: “What about an innocent baby who becomes infected with HIV by its parents and dies from pneumonia? Is that not AIDS?” The fact is that at least as many children die from pneumonia with or without HIV, and it doesn’t significantly influence the outcome of the disease whether they had a previous encounter with HIV or not. What can make a big difference, however, is how the pneumonia is treated.

Different Option of HIV Testing Online

August 10th, 2011

HIV antibody test

The HIV antibody test are the most suitable test for proper diagnosis of HIV among adults. Antibody test are affordable and incredibly correct. The ELISA antibody test (enzyme-linked immunoabsorbent) also referred to as EIA (enzyme immunoassay) was the initial HIV test being widespread.

Just how do antibody tests deliver the results?

When an individual have been infected with HIV, their entire body reacts by generating unique proteins that battles the infection, known as antibodies. A HIV antibody test searches for these antibodies in blood, saliva or urine. If antibodies to HIV are discovered, it indicates that an individual have contracted HIV. There are only two exceptions for this rule:

Infants given birth to a HIV infected mother retain their mother’s antibodies for approximately eighteen months, which suggests they will test positive upon a HIV antibody test, even if they are in fact HIV negative. Generally infants who’re born to HIV positive mothers obtain a PCR test (see below) after birth.

Some individuals who have taken part in HIV vaccine studies might have HIV antibodies even if they’re not have contracted the virus.

A number of people produce noticeable HIV antibodies within 6 to 12 weeks after exposed to the HIV virus. In extremely unusual cases, their can be a 6 months period, and there are almost always very specific causes of antibodies developing so late for instance other auto-immune conditions. It’s extremely unlikely that somebody would take more time than Six months in order to develop antibodies.

A window period of 3 month?

The ‘window period’ is actually a term used to explain the time period between HIV infection and the production of antibodies. During this period, an antibody test can provide a ‘false negative’ end result, meaning the test is going to be negative, despite the fact that an individual have contracted HIV. To prevent incorrect negative results, a second test are suggested after 3 months of possible contact with a HIV infected person..

A negative test at 3 months will more often than not, suggest that an individual have not been infected with HIV. Somebody who is tested and continues to be negative after 6 months, and have not been at risk of HIV infection in the meantime, means they are not infected with HIV.

It is extremely important to notice that if an individual is infected with HIV, they could still transmit the virus to others throughout the window period.

How correct are antibody tests?

Antibody tests are absolutely accurate when it comes to detecting the existence of HIV antibodies. ELISA tests are unquestionably sensitive and therefore will detect a small amount of HIV antibody. This higher level of sensitivity however, means that their specificity (ability to separate HIV antibodies from other antibodies) is marginally reduced. There is for that reason a really modest chance that a result could come back as ‘false positive’.

A false positive result implies that even though an individual might not be infected with HIV, their antibody test may come back positive. All positive test results are followed up by using a confirmatory test, for example:

A Western blot assay – One of the oldest but most precise confirmatory antibody tests. It really is complex to manage and may even generate indeterminate results if an individual carries a transitory infection with a different virus.

An indirect immunofluorescence assay – Like the Western blot, nevertheless it relies on a microscope to detect HIV antibodies.

A line immunoassay – Widely used in the European Union. Minimizes the risk of sample contamination and it is as precise as the Western Blot test.

A 2nd ELISA – In resource-poor settings with comparatively high frequency, a 2nd ELISA test are useful to verify an analysis. The 2nd test will often be a various commercial manufacturer and make use of an alternative technique of recognition to the first.

When two tests are bundled, the possibility of obtaining an incorrect result can be lower than.1%.

Rapid HIV Test

123 Rapid Home Test ( HIV-1/2)

These HIV tests use exactly the same technologies as ELISA tests, but rather then submitting the sample to the clinical for being analysed, the rapid home test generates a results within just Twenty minutes.

Rapid HIV home tests will use either a blood sample or oral fluids. They are really simple to use and don’t require any laboratory facilities or professional staff.

All positive outcomes from a rapid HIV test must be followed up by using a confirmatory test, the final results usually takes from a couple of days to a few weeks.

Antigen test (P24 test)

Antigens will be the substances found in a foreign body or germ that result in the production of antibodies in the entire body. The antigen found in HIV that most commonly brings about an antibody reaction is the protein P24. At the beginning of a HIV infection, P24 is produced in excess and will be detected in the blood serum (even after HIV becomes fully established in the body it will eventually diminish to undetectable concentrations).

P24 antigen tests usually are not used in common HIV diagnostic purposes, as they have a very low level of sensitivity and they only work prior to antibodies are produced in the period right after HIV infection. They are now in most cases utilised as a component of ‘fourth generation’ tests.

Fourth generation tests

The most up to date HIV tests combine P24 antigen tests together with regular antibody tests to scale back the ‘diagnostic window’. Screening for noticeable antibodies and P24 antigen at the same time has the main advantage of enabling earlier and more precise HIV detection.

In the USA, fourth generation tests will be the main suggestion for HIV testing among people, but aren’t provided by all testing sites. In June 2010, the FDA approved the first fourth generation test in the USA.

PCR test

A PCR test (Polymerase Chain Reaction test) can recognize the genetic substance of HIV instead of the antibodies of the virus, and therefore can determine HIV in the blood in just 2 or 3 weeks of an infection. The test is also referred to as a HIV NAAT (nucleic acid amplification tests) or a viral load test.

Babies born to HIV positive parents usually are tested by using a PCR test simply because they sustain their mother’s antibodies for a number of months, making an antibody test incorrect. Blood supplies are generally in most developed nations around the world, screened for HIV using PCR tests. However, they aren’t usually used to test for HIV in men and women, because they are very costly and much more complex to manage and interpret than the regular antibody test.

HIV home screening and HIV home testing

It is usually suggested that the HIV test is performed by a professional medical, However, in many countries home screening and home testing kits are readily available. The quality if this home test kits have improved, and are as safe as the home sampling test and clinical test.

Sampling at Home

Using a home sampling kit, an individual can take a small sample (often a blood sample) and mail it to the clinical for screening. They’re able to phone up for the final results a couple of days afterwards. If the final result is positive then a qualified counsellor will give you emotional assistance and recommendations. The most important benefits of home sampling are convenience, quickness, personal privacy and anonymity.

Home testing

To perform a test at home involves that a man or woman conducting a rapid home screening test for HIV antibody in their own home. The individual takes either a blood or saliva sample and can interpret the result within minutes. A positive result will require a further confirmatory blood-test in a clinic.

In many countries is it legal to sell HIV test kits to the public. If a test is purchased over the internet, check that the test kit is genuine and will provide accurate results. Most serious online websites that offers HIV home test kits, have

There is currently a discussion about permitting the kits to be purchased in The united states and also the United kingdom. The opposition reject legalisation of selling the home testing kits in the united kingdom due to the not enough post-test guidance.